25 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... prematurely • risk of joint ... (muscle/joint) ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Aortic Dissection Pearls
Aortic dissection is caused by a tear in the tunica intima, the innermost layer
is caused by a ... chest/abd/back pain ... Examine for: • Pulse ... deficit/differential ... Dissection #diagnosis #management
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Leg Pain - Differential ... Causes of Leg Pain ... Limb ischemia • Aortic ... refill - Poor pulses ... differential #diagnosis
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... = nonspecific (nausea ... vomiting, abdominal pain ... infiltration) Differential ... iMedEducation #AFLP
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... Clinical Features ... Diagnosis: • A clinical ... Rule out other causes ... #diagnosis #management
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pain Eyes ... Rheumatic fever • Aortic ... Diminished peripheral pulses ... #pain #differential ... #diagnosis #rheumatology
Mallet Finger
Absence of a fracture does NOT exclude Mallet finger, the extension function of the DIP
needs to be clinically ... Finger deformity caused ... fracture • ED Management ... : Pain control, ... Mallet #Finger #Radiology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... - Differential ... Fever/Chills/Joint ... pain/Night sweats ... Loss of signal pulses
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
interphalangeal joint ... with joint-space ... Case description ... Differential diagnosis ... #msk #rheumatology
Freiberg Infraction - MSK Radiology
Imaging Findings:
 • Sclerosis of the 2nd MT head with flattening of
Widening of the MTP joint ... Case description ... • Pain worsens ... Differential diagnosis ... #mri #clinical