21 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... PURPURA: Platelet ... PURPURA: Vasculitis ... Diagnosis #hematology ... #dermatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... purpura (16%) ... purpura • Vesicles ... overlying purpuric ... Henoch-Schönlein purpura
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Crohn's disease Palpable ... purpura • Hypersensitivity ... Henoch Schönlein purpura ... Sarcoidosis #dermatology ... #diagnosis #rheumatology
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
thrombocytopenic purpura ... hemolytic uremic syndrome ... thrombocytopenia, Hematology ... #Diagnosis #Differential
Idiopathic Thrombocytopenic Purpura 
Clinical:
 • Gingival 
 • Menorrhagia 
 • GI bleeding 
 • Intracranial
Thrombocytopenic Purpura ... Clinical: • ... Intracranial hemorrhage Management ... Thrombocytopenic #Purpura ... Diagnosis #Overview #Hematology
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Vessel: Petechiae, Palpable ... purpura, Hemorrhagic ... Disease • Cogan syndrome ... Vasculitis #skin #dermatology ... #rheumatology #
Henoch Schonlein Leg Rash - Palpable Purpura
Purpura: Low Platelets or Vasculitis?
45 years old, seen in our
Purpura Purpura ... Palpable purpura ... Tip: To differentiate ... #Legs #Rash #clinical ... #photo #dermatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
easy bruising to purpura ... (Petechial or purpuric ... 5000 to 10,000 ng/mL ... #Diagnosis #Management ... #Hematology #Rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis: • Purpura ... purpura: Strong ... purpura • Pauci ... purpura, joint ... purpura (lower
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Arthralgia - Purpura ... : • Clinical triad ... of Palpable purpura ... Henoch-Schönlein purpura ... classification #rheumatology