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diagnosis hematology causes differential intravascular syndrome activation behcet classification coagulation cryoglobulinemia cryoglobulins dermatology dic disseminated extravascular hemolysis hemolytic macrophage mas
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... PURPURA: Platelet ... - Hemolytic anemia ... PURPURA: Vasculitis ... Ig A vasculitis/HSP
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Microangiopathic hemolytic anemia ... thrombocytopenic purpura ... (TTP), Hemolytic ... CLL, lymphoma, idiopathic ... #anemia
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
easy bruising to purpura ... (Petechial or purpuric ... with leukopenia, anemia ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Arthralgia - Purpura ... Clinical triad of Palpable ... purpura, Arthralgia ... • Autoimmune diseases ... Henoch-Schönlein purpura
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Petechiae • Purpura ... • Palpable variants ... Hemorrhagic bullae • Purpura ... • Severe Liver Disease ... causes #treatment #management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
multiforme-like lesions, palpable ... purpura, Pathergy ... : Arterial (MCC-small ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
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