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diagnosis hematology syndrome behcet causes coagulation dic differential disease disseminated hemophagocytic hlh intravascular lymphohistiocytosis macrophage mas prs pulmonary renal signs
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... easy bruising to purpura ... (Petechial or purpuric ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... Petechiae • Purpura ... • Palpable variants ... Hemorrhagic bullae • Purpura ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... IFN-y) → Excessive activation ... Phagocytosis of blood ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
multiforme-like lesions, palpable ... purpura, Pathergy ... Arthritis, AS Treatment ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
• Cutaneous: palpable ... purpura 2/2 vasculitis ... reveals increasing blood ... differential #diagnosis #management ... #treatment
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