16 results
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
purpura (16%) ... purpura • Vesicles ... overlying purpuric ... Henoch-Schönlein purpura ... • Goodpasture syndrome
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... Crohn's disease Palpable ... purpura • Hypersensitivity ... Henoch Schönlein purpura ... Antiphospholipid-antibody syndrome
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Henoch Schonlein Purpura ... Rash: - Purpura ... : • Complete blood ... • Fecal occult blood ... cryoglobulins • Skin
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
thrombocytopenic purpura ... content [85].2>5 red blood ... nose (epistaxis), skin ... (alopecia, purpura ... , palpable purpura
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis: • Purpura ... purpura: Strong ... purpura • Pauci ... ) • Palpable purpura ... purpura (lower
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitis: • Purpura ... Henoch Schonlein Purpura ... erythematous nodules, purpura ... purpura: strong ... purpura.
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Arthralgia - Purpura ... Clinical triad of Palpable ... purpura, Arthralgia ... Henoch-Schönlein purpura ... diagnosis #types #classification
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
easy bruising to purpura ... (Petechial or purpuric ... rash) • Heart, ... Fibrin degradation products ... #Diagnosis #Management
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... Demyelinating syndromes ... Glomerulonephritis Myositis(5%) Blood
Primary Dermatological Lesions
Primary lesions are physical changes in the skin considered to be caused directly by
curvilinear lesions produced ... PETECHIAE and PURPURA ... extravascular blood ... Purpura are larger ... and may be palpable