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nephrology diagnosis differential pathology clinical electronmicroscopy nephrotic comparison diseases causes classification glomerulonephritis proteinuria syndrome tuft acute aki hematuria kidneyinjury membranoproliferative
Spectrum of Glomerular Diseases Nephrotic - Mechanism: • Injury to podocytes • Changed architecture: Scanning. Deposition of
Spectrum of Glomerular ... Diseases Nephrotic ... • Injury to podocytes ... other elements Nephritic ... formation #Glomerular
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
Glomerular Diseases ... Nephrotic yndrome—podocyte ... 10 (eg direct podocyte ... damage) or 20 (podocyte ... diabetes)) #Glomerular
Normal Glomerulus on Electron Microscopy This eyeSCANdy image shows scanning EM of normal glomerulus showing glomerular capillary
Normal Glomerulus ... of normal glomerulus ... showing glomerular ... interdigitating podocyte ... arkanalabs #Normal #glomerulus
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 Glomerular Tuft on Electron Microscopy This eyeSCANdy image shows acellular scanning EM of a normal glomerular tuft
Glomerular Tuft ... of a normal glomerular ... removal of the podocytes ... @arkanalabs #glomerulus ... #glomerular #tuft
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 Glomerular Tuft on Electron Microscopy This eyeSCANdy image shows acellular scanning EM of a normal glomerular tuft
Glomerular Tuft ... of a normal glomerular ... removal of the podocytes ... @arkanalabs #glomerulus ... #glomerular #tuft
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 Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
Nephritic vs Nephrotic ... /nephritic syndromes ... the patient have glomerular ... #Nephritic #Nephrotic ... Syndrome #Comparison #Algorithm
Causes of Acute Kidney Injury - Differential Diagnosis Framework Pre-Renal Post-Renal Intrinsic Renal: • Tubules (ATN) • Glomerular:
Tubules (ATN) • Glomerular ... : Nephrotic, Nephritic ... Differential #Diagnosis #Algorithm
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
with evidence of glomerular ... immune deposits in glomeruli ... nephropathy, lupus nephritis ... post-infectious GN Anti-Glomerular ... staining on IF • No EM
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Differential Diagnosis Algorithm ... • Calculi Glomerular ... epithelial side of glomerular ... endothelial side of glomerular ... and >3.5g/day (nephrotic
This image shows scanning EM of a proteinuric glomerulus with capillary loop showing widening and partial
shows scanning EM ... a proteinuric glomerulus ... interdigitating podocyte ... arkanalabs #glomerulus ... ElectronMicroscopy #SEM
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