65 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
RBC casts in urine ... but in severe cases ... Nephrotic yndrome—podocyte ... 10 (eg direct podocyte ... damage) or 20 (podocyte
Spectrum of Glomerular Diseases
Nephrotic - Mechanism:
 • Injury to podocytes
 • Changed architecture: Scanning. Deposition of
Glomerular Diseases Nephrotic ... • Injury to podocytes ... other elements Nephritic ... diagnosis #nephrology #nephritic ... #nephrotic #comparison
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic ... proteinuria, think about nephrotic ... /nephritic syndromes ... hematuria (RBC casts ... #Nephritic #Nephrotic
Differentiation Between Nephrotic Syndrome and Nephritic Syndrome 
== Nephrotic Syndrome ==
Onset - Insidious 
Edema - ++++
Blood
Differentiation Between Nephrotic ... Syndrome and Nephritic ... Syndrome == Nephrotic ... Red blood cell casts ... Red blood cell casts
Causes of Acute Kidney Injury - Differential Diagnosis Framework 
Pre-Renal
Post-Renal
Intrinsic Renal:
 • Tubules (ATN)
 • Glomerular:
Causes of Acute ... • Glomerular: Nephrotic ... , Nephritic • ... #KidneyInjury #Causes
Nephrotic Syndrome - Primary vs Secodary - Differential Diagnosis Algorithm

#Nephrotic #Syndrome #Differential #Diagnosis #Algorithm #Primary #Secondary
Nephrotic Syndrome ... Diagnosis Algorithm #Nephrotic ... Secondary #Nephrology #Causes
Abnormal Lipid Profiles - Differential Diagnosis Algorithm

Increased Cholesterol and Triglycerides 
 - Genetic Causes
- Secondary Causes ... • Nephrotic ... HDL - Genetic Causes ... - Secondary Causes ... Disease • Nephrotic
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... RBCs and/or RBC casts ... • Hereditary nephritis ... and >3.5g/day (nephrotic ... Diagnosis #Algorithm #Causes
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... breakdown of cellular casts ... heme-granular casts ... tubulointerstitial nephritis ... tuberculosis Fatty - Nephrotic
Causes of Generalized Edema - Differential Diagnosis Algorithm
Overfill (Increased renal sodium retention, Urine Na > 40meq/L)
Causes of Generalized ... • AKI/CKD • Nephrotic ... Oncotic Pressure • Nephrotic ... Diagnosis #Algorithm #Causes