9 results
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
leading to an allergic ... Pre-formed lgE binds ... allergen, creating ... an allergen-antibody ... #Immunology #pathophysiology
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... Allergic reaction ... Initial exposure to allergen ... Stevens-Johnson Syndrome ... #Immunology #pathophysiology
Kounis Syndrome (Allergic Angina) - Pathophysiology

#Kounis #Syndrome #Allergic #Angina #Pathophysiology #cardiology
Kounis Syndrome ... (Allergic Angina ... ) - Pathophysiology ... #Allergic #Angina ... #Pathophysiology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
When the specific allergen ... binds to the lgE ... or IgM antibody binds ... Classification #Pathophysiology ... #Allergy #Diagnosis
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
Pathophysiology ... Hyperglycemic Hyperosmolar Syndrome ... infections, food binges ... #dka #hhs #pathophysiology
Allergic Rhinitis: Pathogenesis and clinical findings

1. Allergy Sensitization -> Antigen Exposure -> APC (macrophages, HLA class
Allergic Rhinitis ... Allergy Sensitization ... Exposure -> Antigen binds ... Tissue edema #Allergic ... Rhinitis #Rhinorrhea #pathophysiology
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
Antigen binds receptor ... (i.e. heparin) binds ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Peripheral Edema - Differential Diagnosis Framework for Lower Extremity Edema

Edema occurs when any of the following
• May-Thurner Syndrome ... regional pain syndrome ... • SVC syndrome ... Non-pitting) • Allergic ... #PhysicalExam #Pathophysiology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
constipation • Allergic ... Stevens-Johnson Syndrome ... #SideEffects #Pathophysiology