2973 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... nephrocalcinosis • CPPD ... • Inorganic pyrophosphate ... PPi (inorganic pyrophosphate ... Phosphatase: • Other causes
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
vast majority of cases ... ANKH gene, Incr pyrophosphate ... dihydrate (CPPD ... and/or x-ray - CPPD ... Chondrocalcinosis #Pseudogout #CPPD
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
CPPD vs Gout ... == CPPD == Think ... About CPPD When ... Pathophysiology: • Pyrophosphate ... Asymptomatic CPPD
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Summary - Calcium Pyrophosphate ... Pathophysiology: Pyrophosphate ... calcium to form CPP ... Chronic calcium pyrophosphate ... #Calcium #Pyrophosphate
Drugs Causing Acute Pancreatitis

Class Ia: The medications in which there was a rechallenge and other causes
rechallenge and other causes ... out other common causes ... Class II: Cases ... and atleast4 case ... #Pancreatitis #Causes
Pathogens in Pneumonia

Here is a quick review of the pathogens causing pneumonia (useful for enumerating differentials
your grand rounds/cases ... H. influenzae (COPD ... Pseudomonas — COPD ... Legionella spp (COPD ... #Microbiology #Causes
Causes of Chronic Dyspnea - Differential Diagnosis Algorithm
Pericardial
 • Effusion
 • Cardiac Tamponade*
 • Constriction
Myocardial
 •
Causes of Chronic ... • Asthma • COPD ... Pleural Thickening/Masses ... Pneumonia • ARDS • COPD ... Diagnosis #Algorithm #Causes
Tachypnea - Differential Diagnosis Framework

Definitions
 • Tachypnea: Respiratory rate > 20/min, shallow breathing in adults
 •
breathing Pulmonary Causes ... • Asthma • COPD ... PVFM) Cardiac Causes ... Hematologic Causes ... acidosis of any cause
Causes of Erythema Nodosum - Mnemonic

NO cause found in 60% of cases
Drugs (antibiotics e.g., sulfonamides, amoxicillin)
Oral
Causes of Erythema ... Mnemonic NO cause ... found in 60% of cases ... Nodosum #Mnemonic #Causes
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
Cardiovascular Causes ... Tamponade Pulmonary Causes ... - Asthma - COPD ... syndrome Other Causes ... differential #diagnosis #causes