292 results
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
vast majority of cases ... ANKH gene, Incr pyrophosphate ... dihydrate (CPPD ... and/or x-ray - CPPD ... Chondrocalcinosis #Pseudogout #CPPD
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
CPPD vs Gout ... == CPPD == Think ... About CPPD When ... Pathophysiology: • Pyrophosphate ... Asymptomatic CPPD
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Summary - Calcium Pyrophosphate ... Pathophysiology: Pyrophosphate ... calcium to form CPP ... Chronic calcium pyrophosphate ... #Calcium #Pyrophosphate
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... nephrocalcinosis • CPPD ... • Inorganic pyrophosphate ... PPi (inorganic pyrophosphate ... Phosphatase: • Other causes
Pathogens in Pneumonia

Here is a quick review of the pathogens causing pneumonia (useful for enumerating differentials
your grand rounds/cases ... H. influenzae (COPD ... Pseudomonas — COPD ... Legionella spp (COPD ... #Microbiology #Causes
Causes of Chronic Dyspnea - Differential Diagnosis Algorithm
Pericardial
 • Effusion
 • Cardiac Tamponade*
 • Constriction
Myocardial
 •
Causes of Chronic ... • Asthma • COPD ... Pleural Thickening/Masses ... Pneumonia • ARDS • COPD ... Diagnosis #Algorithm #Causes
Tachypnea - Differential Diagnosis Framework

Definitions
 • Tachypnea: Respiratory rate > 20/min, shallow breathing in adults
 •
breathing Pulmonary Causes ... • Asthma • COPD ... PVFM) Cardiac Causes ... Hematologic Causes ... acidosis of any cause
Campbell’s sign or Tracheal Descent in Longstanding COPD

Patients with longstanding COPD may show downward displacement of
in Longstanding COPD ... with longstanding COPD ... Tracheal #Descent #COPD ... #clinical #video
Tracheal Descent Sign

Paradoxical inward movement of the trachea during inspiration. Seen in this COPD patient in
Seen in this COPD ... Video via Dr. ... Sign #clinical #video ... breathing #Trachea #COPD
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
Cardiovascular Causes ... Tamponade Pulmonary Causes ... - Asthma - COPD ... syndrome Other Causes ... differential #diagnosis #causes