2345 results
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
ANKH gene, Incr pyrophosphate ... dihydrate (CPPD ... activity, reduces pyrophosphate ... and/or x-ray - CPPD ... Chondrocalcinosis #Pseudogout #CPPD
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
CPPD vs Gout ... == CPPD == Think ... About CPPD When ... Pathophysiology: • Pyrophosphate ... Asymptomatic CPPD
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Summary - Calcium Pyrophosphate ... Pathophysiology: Pyrophosphate ... calcium to form CPP ... Chronic calcium pyrophosphate ... #Calcium #Pyrophosphate
Pathogens in Pneumonia

Here is a quick review of the pathogens causing pneumonia (useful for enumerating differentials
for enumerating differentials ... H. influenzae (COPD ... Pseudomonas — COPD ... Legionella spp (COPD ... Pathogens #Pneumonia #Differential
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Joint Disorders - Differential ... Pseudogout” - Calcium Pyrophosphate ... Disorders #msk #Differential
Seronegative Inflammatory Arthritis - Differential Diagnosis
 • Seronegative Rheumatoid Arthritis 
 • Infectious Arthritis: Viral, Bacterial,
Inflammatory Arthritis - Differential ... Arthropathy: Gout, CPPD ... #arthritides #Differential
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
nephrocalcinosis • CPPD ... • Inorganic pyrophosphate ... PPi (inorganic pyrophosphate
Acute Hypoxemia - Differential Diagnosis
 • Hyperacute: Aspiration, Flash Pulmonary Edema, Mucous Plugging, Bronchospasm, Pulmonary Embolism,
Acute Hypoxemia - Differential ... pHTN, Advanced COPD ... Disease: Asthma, COPD ... Hypoxemia #hypoxia #Differential
Monoarthritis - Differential Diagnosis
Infection (Acute):
 - S. aureus (most common)
 - S. pneumonia
 - Salmonella (in
Monoarthritis - Differential ... birefringent - CPPD ... Monoarthritis #Differential
First-line therapies for Asthma, Asthma-COPD Overlap and COPD

The diagnosis of COPD, asthma, and ACO initially requires
Asthma, Asthma-COPD ... Overlap and COPD ... The diagnosis of COPD ... summary of the differential ... ACO = asthma-COPD