84 results
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
ANKH gene, Incr pyrophosphate ... dihydrate (CPPD ... activity, reduces pyrophosphate ... and/or x-ray - CPPD ... Chondrocalcinosis #Pseudogout #CPPD
Hypophosphatemia and Hypoxia - Pathophysiology

↓ Phosphate leads to ↓ red cell 2,3-DPG and a  reduction
function is respiratory ... Respiratory muscle ... phosphorus is seen in COPD ... patients with COPD ... Respiratory muscles
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
CPPD vs Gout ... == CPPD == Think ... About CPPD When ... Pathophysiology: • Pyrophosphate ... Asymptomatic CPPD
Noninvasive Positive Pressure Ventilation (NIPPV)

Expiratory & Inspiratory Positive Airway Pressure
Both increase intrathoracic pressure, which can decrease
In COPD, decreases ... pulmonary edema) • COPD ... patients (ie., CHF or COPD ... • Other acute respiratory ... exacerbation) • Chronic respiratory
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Summary - Calcium Pyrophosphate ... Pathophysiology: Pyrophosphate ... calcium to form CPP ... Chronic calcium pyrophosphate ... #Calcium #Pyrophosphate
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
nephrocalcinosis • CPPD ... • Inorganic pyrophosphate ... PPi (inorganic pyrophosphate ... Phosphatase: • Respiratory ... : - respiratory
Tracheal Descent Sign

Paradoxical inward movement of the trachea during inspiration. Seen in this COPD patient in
Seen in this COPD ... patient in severe respiratory ... #physicalexam #respiratory ... breathing #Trachea #COPD
A Non-Invasive approach to Respiratory Failure
 • COPD and Ventilatory Failure → NiPPV with Bi-level Settings
Non-Invasive approach to Respiratory ... Failure • COPD ... #NonInvasive #Respiratory
First-line therapies for Asthma, Asthma-COPD Overlap and COPD

The diagnosis of COPD, asthma, and ACO initially requires
Asthma, Asthma-COPD ... Overlap and COPD ... The diagnosis of COPD ... of exposure to respiratory ... and pattern of respiratory
Campbell’s sign or Tracheal Descent in Longstanding COPD

Patients with longstanding COPD may show downward displacement of
in Longstanding COPD ... with longstanding COPD ... Tracheal #Descent #COPD ... physicalexam #pulmonary #respiratory