27 results
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
gene mutated in all ... Retinoblastoma Signs / Symptoms ... Retinoblastoma #pathophysiology ... #ophthalmology ... diagnosis #signs #symptoms
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
damaged BRB appears as ... of the terminal retinal ... #Retinopathy #pathophysiology ... #ophthalmology ... diagnosis #signs #symptoms
Orbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Chemosis: Edema of the bulbar conjunctiva
b. Panopthalmitis: inflammation of all
inflammation of all ... -> Corneal drying ... Orbital #Cellulitis #pathophysiology ... #ophthalmology ... diagnosis #signs #symptoms
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Dehydration • Symptoms ... , AKI, acute limb ... Lysis Syndrome: • Pathophysiology
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... → Inflammation causes ... functional ID) Treatment ... improvement in symptoms ... composite endpoint of all-cause
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
adult population: also ... collection with EDTA Pathophysiology ... mineralization Symptoms ... respiratory failure • Neurologic ... Phosphatase: • Other causes
Diplopia - Double Vision - Differential Diagnosis Algorithm
Clinical Pearls:
 • Diplopia is almost always binocular.
 •
Neurologic ... symptoms suggest ... a mass as the cause ... Functional • Corneal ... #Ophthalmology
All About Horner's Syndrome

Horner's syndrome, known as 
"oculosympathetic paresis" by people 
who don't have friends, is
All About Horner's ... have friends, is caused ... in 1855 by Ed Horner ... Syndrome #Overview #Ophthalmology ... #Diagnosis #Neurology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Management Summary Causes ... : • Triad of symptoms ... 5X ULN • AST/ALT ... AST declines > ALT ... #treatment #nephrology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Lateral Sclerosis (ALS ... lateral sclerosis Pathophysiology ... - Causes progressive ... fasciculations Common Symptoms ... diagnosis column Treatment