132 results
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
/ Normochromic RBCs ... on Smear • Chronic ... TIBC, Hypochromic RBCs ... Decreased RBC ... Spherocytes on Smear
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases

Acanthocyte (spur cell),  
Basophilic stippling, 
Bite cell,
Pathologic Red Blood ... Cell (RBC) Morphologies ... cell, Other RBC ... Howell-Jolly bodies #RBC ... Atlas #Microscopy #Pathology
Plasmodium Falciparum Blood Smear.
Key features suggesting Plasmodium falciparum:
- extreme parasitemia
- normocytic RBCs (vivax, ovale prefer big
Falciparum Blood Smear ... parasitemia - normocytic RBCs ... multiples per RBC ... rare in blood smears ... Falciparum #Blood #Smear
Plasmodium - Identification Algorithm
 • P. falciparum: RINGS AND GAMETOCYTES PREDOMINATE, Small delicate rings, <1/3 size
rings, <1/3 size RBC ... Multiple rings/RBC ... rings, ≤ 1/3 size RBC ... Identification #Algorithm #pathology ... #smear #microscopy
Beautiful acanthocytes/spur cells in a patient with McLeod Syndrome. X-linked disorder characterized by reduced expression of
expression of Kell RBC ... McLeod #Syndrome #Smear ... #Pathology #Microscopy
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
2) External (RBC ... 3) Internal (RBC ... Peripheral Blood Smear ... ↑ abnormal RBCs
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
glomerular hematuria (RBC ... or dysmorphic RBCs ... Comparison #Algorithm #Nephrology
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
red blood cells (RBCs ... serum due to the RBCs ... #Path #Blood #Smear ... #Microscopy #RBC
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
red blood cells (RBCs ... serum due to the RBCs ... #Path #Blood #Smear ... #Microscopy #RBC
Red Blood Cell Morphology Atlas

Size variation, Hemoglobin distribution,  
Hypochromia,  
Shape variation,  
Inclusions, 
Red
#Path #Blood #Smear ... #RBC #Morphology