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ATHOS-3 - Angiotensin II for the Treatment of Vasodilatory Shock

Khanna A et al. "Angiotensin II for
ATHOS-3 - Angiotensin ... II for the Treatment ... for the Treatment ... VisualAbstract #EBM #CriticalCare ... #Shock
Shock Types and Classification
DISTRIBUTIVE 66%
 • Sepsis/SIRS, anaphylaxis, adrenal insufficiency, liver failure, toxins, spinal/neurogenic
 • Warm
Shock Types and ... • Bleed (GIB, RP ... Cold and Dry #Shock ... #differential #criticalcare
Vasopressors and Inotropes
 • Norepinephrine - Levophed - "Levo" - Generally thought of as the first
pressor added in shock ... in refractory shock ... in setting of shock ... tine anymore) • Angiotensin ... Inotropes #management #criticalcare
Causes, classification and compensatory responses to shock.

Shock can be caused by any pathological process that leads
compensatory responses to shock ... Shock can be caused ... The cause of shock ... RAAS, renin–angiotensin–aldosterone ... #Diagnosis #CriticalCare
Algorithm for the management of severe or refractory anaphylaxis and related airway and vascular complications in
anaphylaxis and related airway ... Algorithm #management #criticalcare ... #treatment
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Shock - Differential ... Dehydration Shock ... Treatment Goals ... Differential #Diagnosis #criticalcare ... #algorithm #treatment
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Shock Overview ... of hypotension Shock ... Distributive Shock ... RP bleed) • Hypovolemic ... management #Overview #criticalcare
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Shock Overview ... of hypotension Shock ... Distributive Shock ... RP bleed) • Hypovolemic ... management #Overview #criticalcare
Shock - Diagnosis and Management Summary
 • Hypotension: SBP<90, SBP drop >40, MAP<65 (Normotension, HTN possible
Shock - Diagnosis ... possible w/ early shock ... • Obstructive Shock ... Management #Summary #criticalcare ... #treatment #workup
Summary of Infections in which Steroids play a role in treatment
 • TB meningitis
 • TB
play a role in treatment ... Refractory septic shock ... mononucleosis with airway ... infections #management #treatment