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diagnosis differential management causes defects rhabdomyolysis treatment bartter epithelial fanconi hypokalemia hyponatremia hypotonic inherited kidney liddle localization nephron physiologic sodium
Localization of Renal Tubular Defects Fanconi Syndrome: Proximal tubule Bartter Syndrome: Thick ascending loop of Henle Gitelman Syndrome: Distal
Localization of Renal ... loop of Henle Gitelman ... Fanconi #Bartter #Gitelman ... Nephron #Defects #Pathophysiology ... #Nephrology
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
Epithelial Cells Renal ... ascending limb Gitelman ... receptor Distal renal ... Defects #Kidney #Nephrology ... #Differential #Table
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
≥100): SIADH, Renal ... Losses (AKI, Post-AKI ... Cirrhosis, Nephrotic syndrome ... differential #diagnosis #table ... #sodium #nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... • Hypokalemia (renal ... , Renal tubular ... #nephrology #management ... #pathophysiology
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
iniury, Compartment syndrome ... Neuroleptic malignant syndrome ... Dermatomyositis) AKI ... - Pathophysiology ... per day until stable
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Compartment syndrome ... declines > ALT) • AKI ... + myoglobin AKI ... per day until stable ... causes #treatment #nephrology
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