11 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... months without treatment ... Infections Alcohol-Associated ... Injury (DILI) ... #Hepatology #gastroenterology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... non-essential drug/HDS treatments ... for alternative causes ... HEV, EBV, CMV), Alcohol-related ... #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Algorithm Vascular Causes ... • Iatrogenic: DILI ... ALT Ratios: • Alcoholic ... diagnosis #algorithm #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
acid metabolism products ... = nonspecific (nausea ... failure rapidly ... 10x ULN), ↑Tbili/Dbili ... #Pregnancy #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Failure (ALF): ... • Liver injury ... ALT Ratios: • Alcoholic ... Unconjugated Bili ... #differential #Hepatology
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... exclude other causes ... - Acute kidney injury ... HCV, DILI, HCC, ... Management #Algorithm #hepatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
or renal injury ... perfusion - shock->treatments ... before beginning treatment ... Hypoglycemia - Alcohol ... Injury: • Reduced
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
hypoTN, renal failure ... Causes purpura & ... Related Acute Lung Injury ... TRALI): Leading cause ... eruptions, diarrhea, liver
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
hypoTN, renal failure ... Causes purpura & ... Related Acute Lung Injury ... TRALI): Leading cause ... eruptions, diarrhea, liver
Complications after Bariatric Surgery
Post Bariatric Intestinal Failure:
 • Severe protein malnutrition after bariatric surgery
 • More
nutrients • TPN for treatment ... Gastric bypass causes ... Liver Disease in ... metronidazole • Alcohol ... Gastroenterology and Hepatology