13 results
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects ... in Kidney Tubule ... ascending limb Gitelman ... #Nephrology #Diagnosis ... #Differential #Table
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Primary Metabolic ... - Differential Diagnosis ... Bartter Syndrome, Gitelman ... hyperaldosteronism • High PRA: Renal ... #Algorithm #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
alkalosis • Kidney ... Cl- outside the kidneys ... Bartter syndrome, Gitelman ... #Algorithm #nephrology ... #differential #diagnosis
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... - Differential Diagnosis ... Bartter Syndrome, Gitelman ... hyperaldosteronism • High PRA: Renal ... #Algorithm #Nephrology
Gitelman Syndrome - Diagnosis and Workup
Blood Work:
 - Hypokalemia
 - Hypomagnesemia
 - Metabolic Alkalosis
 - Elevated
Gitelman Syndrome ... Hypomagnesemia - Metabolic ... Elevated Renin Urine ... of echogenic kidneys ... #Workup #nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
differentiating kidney ... A urine K/Cr ratio ... suggests extra-renal ... Bartter syndrome, Gitelman ... #Hypokalemia #diagnosis
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Inherited (AR) ... • Hypokalemia (renal ... Hypocalciuria (spot urine ... Sjögren syndrome, Renal ... #Syndrome #diagnosis
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
- Differential Diagnosis ... - Diarrhea • RENAL ... - Bartter - Gitelman ... gas transport, renal ... unloading • Kidney
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
: Differential Diagnosis ... diuretics after renal ... furosemide-like lesion) • Gitelman ... #Differential #Diagnosis ... #Causes #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... - Differential Diagnosis ... Bartter Syndrome, Gitelman ... hyperaldosteronism • High PRA: Renal ... #Algorithm #Nephrology