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diagnosis lupus differential druginduced hematology summary treatment dil disorders erythematosus hemophagocytic hlh hodgkins lymphohistiocytosis lymphoma oncology platelet sjogrens syndrome systemic
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... • Immunologic Workup ... #comparison #table ... #rheumatology # ... diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... • Immunologic Workup ... Positive in 60-80% of cases ... Usual therapeutic management ... #Summary #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... Diagnosis and Workup ... decreased PLT count: CBC ... test, ANA (e.g., SLE ... #Workup #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... Autoimmune diseases: SLE ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
) Classification ... Hodgkin Lymphoma Workup ... lymphoma #diagnosis #classification ... #hematology #oncology ... #management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... Lab Tests: • CBC ... vasculitis, and SLE ... differential #diagnosis #rheumatology ... #classification
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Hypocomplementemia • Can cause ... /aggregate) of CD4 ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
is rare in DIL, SCLE-DIL ... • Immunologic Workup ... Discontinuation of causal ... DrugInduced #Lupus #DIL #rheumatology ... diagnosis #treatment #management
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