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diagnosis hematology differential gammopathy mgus agglutinin cell clinical cold disease gap globulin hemolytic hodgkins lymphoma management mds myelodysplasia myelodysplastic plasmacytoma
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
of Clinical Significance ... immunotactoid GN, Type ... Gammopathy #Clinical #Significance ... Differential #Diagnosis #hematology ... #oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
of Undetermined Significance ... No evidence of anemia ... level (non-IgM type ... insufficiency, Anemia ... #oncology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Disease 3 Types ... • Symptoms of anemia ... • hemolytic anemia ... of undetermined significance ... #hematology #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... of Undetermined Significance ... of Undetermined Significance ... Workup: • Complete ... #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... -95% of cases) Classification ... Hodgkin Lymphoma Workup ... #hematology #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... it represents a monoclonal ... Causes of Monoclonal ... Thalassemia, Sickle cell anemia ... Comment on type
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
tissue composed of monoclonal ... • No CRAB - no anemia ... #Plasmacytoma #Oncology ... #Diagnosis #Workup ... #Hematology
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