23 results
Differential Diagnosis of Hypoglycemia
Evaluation of Hypoglycemia
Patients with known diabetes who are not systemically ill and can
- LFT - EtOH - Infectious ... blood cultures - ECG ... antibodies #Diagnosis #EM
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors - Pharmacology ... Weight loss (~2-3kg ... hypovolemia) • GU infections ... (e.g. ... SGLT2 #Inhibitors #Pharmacology
IDSA Recommendations for Treating Visceral and Cutaneous Leishmaniasis in HIV-AIDS
Treating Visceral Leishmaniasis - Preferred Therapy:
 •
., 4 mg/kg on days ... dose of 20–60 mg/kg ... ., 4 mg/kg on days ... opportunistic #infections ... #HIVAIDS #pharmacology
Coverage of common antibiotics used in the hospital

For empiric coverage, first define the type of infection,
define the type of infection ... prior resistance. e.g ... #antibiogram #pharmacology
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
Receptor Agonists - Pharmacology ... /day or weekly injection ... Victoza) - Daily injection ... side effects (e.g ... Receptor #Agonists #Pharmacology
IDSA Recommendations for Preventing and Treating Penicillium marneffei Infections in HIV-AIDS
Preventing 1st Episode of Penicilliosis (Primary
Penicillium marneffei Infections ... Treating Acute Infection ... amphotericin B, 3 to 5 mg/kg ... opportunistic #infections ... #HIVAIDS #pharmacology
Modified penicillin binding proteins as mechanism of resistance to antibiotics.
Penicillin Binding Proteins (Transpeptidases) cross link peptidoglycan
more antibiotic (e.g ... amox for an ear infection ... cephalosporin (e.g ... vancomycin to CTX (e.g ... Proteins #AMR #PBP #pharmacology
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
• Malignancy Infectious ... Myasthenia Gravis Pharmacologic ... • Drug Abuse (e.g
Anti-IL6 Agents (Tocilizumab, Siltuximab) in COVID19

IL-6 activates T cells and macrophages, among other cell types (see
Tocilizumab 4-8mg/kg ... respiratory tract infection ... Siltuximab 11mg/kg ... Siltuximab #COVID19 #Pharmacology
IDSA Recommendations for Preventing and Treating Chagas Disease (American Trypanosomiasis) in HIV-AIDS
Preventing Clinical Disease
Indication:  Individuals
Benznidazole 5–8 mg/kg ... Nifurtimox 8–10 mg/kg ... opportunistic #infections ... #HIVAIDS #pharmacology