7 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... , Arthralgia/arthritis ... Complications: MAS ... Disease #diagnosis #management ... #treatment #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
juvenile idiopathic arthritis ... • Adult-onset Still ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... mL Gf consider MAS ... Treatment - Mild ... AOSD #diagnosis #rheumatology ... #management
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... refractory disease Arthritis ... case) • Surgery may ... #Treatment #management ... #pharmacology #rheumatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Acute Pseudogout: Treatment ... Crowned Dens Syndrome ... acute neck pain, fever ... Deposition #Disease #Rheumatology ... #diagnosis #management
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
Diagnosis and Management ... sex • Metabolic syndrome ... 12-24 Hours • Fever ... frequent attacks • Arthritis ... #treatment #rheumatology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
respiratory symptoms • Fever ... , cough, chills, ... pulmonary symptoms • Rheumatologic ... Meningitis, septic arthritis ... Fungal #Diagnosis #Management