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Differential diagnosis of Langerhans cell histiocytosis.
Nodular LCH:
- Sarcoidosis: perilymphatic distribution.
- Metastases: random distribution.
Cystic LCH:
- LAM: round

Differential diagnosis ... Clinical #Diagnosis #Radiology ... #CTChest #Cystic ... #Cysts #Differential ... Comparison #Table #RadiologyAssistant

Perilymphatic distribution
Perilymphatic nodules are most commonly seen in sarcoidosis.
They also occur in silicosis, coal-worker's pneumoconiosis and

the overlap in differential ... #Diagnosis #Radiology ... Pulmonary #HRCT #CTChest ... Perilymphatic #Nodular #Differential ... #RadiologyAssistant

The fourth pattern includes abnormalities that result in decreased lung attenuation or air-filled lesions.
These include:
- Emphysema
-

#Diagnosis #Radiology ... #Pulmonary #CTChest ... LowAttenuation #Differential ... Emphysema #SignetRing #RadiologyAssistant

Tree-in-bud
In centrilobular nodules the recognition of 'tree-in-bud' is of value for narrowing the differential diagnosis.
Tree-in-bud describes

narrowing the differential ... Diagnosis #Pathophys #Radiology ... #Pulmonary #CTChest ... TreeInBud #Diagram #RadiologyAssistant

Consolidation is synonymous with airspace disease.
When you think of the causes of consolidation, think of 'what

#Diagnosis #Radiology ... #Pulmonary #CTChest ... Consolidation #Differential ... #RadiologyAssistant

Tree-in-bud almost always indicates the presence of:
Endobronchial spread of infection (TB, MAC, any bacterial bronchopneumonia)
Airway disease

#Diagnosis #Radiology ... #Pulmonary #CTChest ... #TreeInBud #Differential ... #RadiologyAssistant

On the left some diseases with a nodular pattern.
1. Hypersensitivity pneumonitis: ill defined centrilobular nodules.
2. Miliary

Clinical #Diagnosis #Radiology ... #Pulmonary #CTChest ... NodularPattern #Differential ... Comparison #Table #RadiologyAssistant

Ground-glass opacity
Ground-glass opacity (GGO) represents:
- Filling of the alveolar spaces with pus, edema, hemorrhage, inflammation or

bronchiolitis #Diagnosis #Radiology ... #Pulmonary #CTChest ... #GroundGlass #Differential ... #RadiologyAssistant

Algorithm for nodular pattern
The algorithm to distinguish perilymphatic, random and centrilobular nodules is the following:
- Look

#Diagnosis #Radiology ... Pulmonary #HRCT #CTChest ... MultipleNodules #Nodules #Differential ... #Algorithm #RadiologyAssistant

Differential diagnosis of TB.
Primary TB: Acute bacterial pneumonia
Secondary TB: Sarcoidosis, Silicosis, Pneumoconiosis
Endobronchial spread of TB: Bronchopneumonia,

Differential diagnosis ... Clinical #Diagnosis #Radiology ... #CTChest #MiliaryTB ... Metastases #Mimic #RadiologyAssistant

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