15 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... presentation • Chronic ... #differential #Diagnosis ... #Management #gastroenterology ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... Injury (DILI) ... #Cirrhosis #Hepatology ... #gastroenterology ... #management #diagnosis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... non-essential drug/HDS treatments ... e.g. ascites), Chronic ... #Injury #Diagnosis ... #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... • Iatrogenic: DILI ... > 2 • NASH, Chronic ... injury: > 3 • Chronic ... #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
ALT AST:ALT Ratios ... > 2 • NASH, Chronic ... injury: > 3 • Chronic ... #chemistry #diagnosis ... #differential #Hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
B - Diagnosis and ... Management Algorithm ... HBV #Algorithm #Diagnosis ... #Management #Treatment ... #Hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
disease to acute liver ... - Symptoms of chronic ... Viral) Management ... regarding need for treatment ... #Management #Hepatology
Gastroesophageal Reflux Disease (GERD) - Summary

GERD: Diagnosis
• Heartburn (substernal burning sensation) and acid regurgitation
• Chest pain
Extraesophageal
Summary GERD: Diagnosis ... throat clearing, chronic ... Incomplete/relief/treatment ... Reflux #Disease #diagnosis ... #management #Gastroenterology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
regarding the diagnosis ... and treatment of ... hemochromatosis #algorithm #diagnosis ... #management #hepatology ... #gastroenterology
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
PSC) PSC is a chronic ... asymptomatic at diagnosis ... liver disease management ... #management #summary ... #Hepatology