14 results
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia
Clinical
 - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
Secondary to sustained immune ... - Positive: CD2 ... , CD3, CD8 - Loss ... of CD5 and/or CD7 ... hemepath #pathology #diagnosis
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
reaction - Atopic disease ... CD3-CD4+ T cells ... , IgG4-related disease ... malignancy - Immune ... #Differential #Diagnosis
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
occur when the CD4 ... required until immune ... recovery (CD4-cell ... Demyelinating disease ... Lymphoma: • CD4
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
ART ↑ improves CD4 ... low pretreatment CD4 ... an increase in CD4 ... Depends On: • CD4 ... suppression • CD4
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... that disrupts immune ... • Autoimmune diseases ... Adult-onset Still disease ... Others: Cellular immune
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
during transient CD4 ... manifestations Labs: • CD4 ... in which case opportunistic ... ART to slow HIV disease ... progression by slowing CD4
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
rendering the immune ... phenomenon CLL Diagnosis ... cells can indicate disease ... surface molecules: CD5 ... Lymphocytic #Leukemia #diagnosis
Amebiasis - Balamuthia mandrillaris Life Cycle
1) Cysts
2) Trophozoite
3) Mitosis
4) Amebae (cysts and trophozoites) can enter humans
, disseminated disease ... individuals who are immune ... with compromised immune ... mandrillaris #LifeCycle #diagnosis ... infectiousdiseases #cdc
Amebiasis - Acanthamoeba Life Cycle
1) Cysts
2) Trophozoite
3) Mitosis
4) Amebae (cysts and trophozoites) can enter humans in
or disseminated disease ... with compromised immune ... , disseminated disease ... Acanthamoeba #LifeCycle #diagnosis ... infectiousdiseases #cdc
IDSA Recommendations for Preventing and Managing Microsporidiosis in HIV-AIDS
Preventing Chronic Microsporidiosis:
 • Because chronic microsporidiosis occurs
should prevent the disease ... optimize ART with immune ... restoration to CD4 ... patients with low CD4 ... Treatment #management #opportunistic