8 results
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Immune Reconstitution ... Inflammatory Syndrome ... after initiating antiretroviral ... with exaggerated inflammatory ... #Syndrome #Differential
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
• CNS opportunistic ... after combination antiretroviral ... • Combination antiretroviral ... required until immune ... achieved with antiretroviral
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Guillain-Barré syndrome ... antisynthetase syndrome ... , immune-mediated ... Statins → Inflammatory ... Diagnosis: • CK
Immune Reconstitution Inflammatory Syndrome (IRIS) - Pathophysiology
Risk factors:
 - Low CD4 count
 - Disseminated OI
 -
Immune Reconstitution ... Inflammatory Syndrome ... factors: - Low CD4 ... - Paucity of inflammatory ... #Syndrome #IRIS
Neurological Manifestations of Tuberculosis
Spinal Arachnoiditis & Polyradiculopathy:
 • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
narrowing and collapse Immune ... Reconstitution Inflammatory ... Syndrome (IRIS) ... after starting antiretroviral ... symptoms • Caused by immune
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
• Acute stroke syndromes ... Paraneoplastic syndrome ... • Inflammatory ... Polymyositis • Immune ... Up: • Chem: CPK
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
leads to an acute inflammatory ... sex • Metabolic syndrome ... fingers, wrist, elbow ... Tophi on extensor elbows ... attack + stage ≥3 CKD
Celiac disease is an immune-mediated, multisystem disorder that affects genetically susceptible individuals who are exposed to
disease is an immune-mediated ... inappropriate immune ... CD can be associated ... and William’s syndromes ... surfaces, such as the elbows