19 results
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
: • Most CNS opportunistic ... • CNS opportunistic ... Demyelinating disease ... - Generally >3 cm ... and <25% culture positive
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... HBV, Coxsackie, CMV ... autoinflammatory diseases ... Muscular: normal CK ... #diagnosis #management
IDSA Recommendations for Preventing and Treating Chagas Disease (American Trypanosomiasis) in HIV-AIDS
Preventing Clinical Disease
Indication:  Individuals
Treating Chagas Disease ... Preventing Clinical Disease ... and tested positive ... Prevention #Treatment #management ... #opportunistic
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
worsening of that disease ... previously diagnosed opportunistic ... pericarditis, peritoneal disease ... keratitis, iritis • CMV ... Differential #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... +: Virus (EBV, CMV ... • Autoimmune diseases ... or biologics (CMV ... Lymphohistiocytosis #diagnosis #management
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
Presentations: • Opportunistic ... during transient CD4 ... in which case opportunistic ... Cytomegalovirus (CMV ... ART to slow HIV disease
IDSA Recommendations for Treating Cytomegalovirus Infections in HIV-AIDS
Preventing CMV Disease:
 • CMV end-organ disease is best
Disease: • CMV ... end-organ disease ... ART to maintain CD4 ... Prevention #Treatment #management ... #opportunistic
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary
Chagas disease (American trypanosomiasis) is an infectious
Chagas Disease - ... Diagnosis and Management ... signs/symptoms, positive ... only available at CDC ... Trypanosomiasis #Diagnosis #Management
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... pain Labs: • CPK ... Myoglobinuria: UA positive ... of underlying disease ... Differential #Diagnosis #Management
IDSA Recommendations for Preventing and Treating Toxoplasma gondii Encephalitis in HIV-AIDS
Indications for Initiating Primary Prophylaxis:
 •
Toxoplasma IgG positive ... patients with CD4 ... Prevention #Treatment #opportunistic ... infections #HIVAIDS #management