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diagnosis differential treatment hematology hiv infectiousdiseases aids hivaids idsa pharmacology prevention activation acute adultonset agglutinin anemia autoimmune behcet calcium causes
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
CNS Infection in ... Opportunistic Infections ... : • Most CNS opportunistic ... opportunistic infections ... • CNS opportunistic
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Diaqnoses: • Infectious ... HBV, Coxsackie, CMV ... Muscular: normal CK ... #diagnosis #management ... #treatment #rheumatology
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
Acute Retroviral Syndrome ... Presentations: • Opportunistic ... in which case opportunistic ... Cytomegalovirus (CMV ... ART to slow HIV disease
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... +: Virus (EBV, CMV ... or biologics (CMV ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
basal ganglia, CNS ... meningitis), MCC CNS ... Skin lesions • Positive ... #diagnosis #management ... signs #symptoms #rheumatology
IDSA Recommendations for Treating Cytomegalovirus Infections in HIV-AIDS Preventing CMV Disease: • CMV end-organ disease is best
Disease: • CMV ... end-organ disease ... ART to maintain CD4 ... Prevention #Treatment #management ... #opportunistic
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... worsening of that disease ... pleural effusions, CNS ... keratitis, iritis • CMV ... Differential #Diagnosis #Management
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... (CAS): - Due ... to Viral infection ... dehydrogenase • Positive ... hemolytic #anemia #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... nervous system (CNS ... SLE], AOSD) • Infection ... #Diagnosis #Management ... #Hematology #Rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... involvement • 30%: CNS ... develop leukostasis syndrome ... : CNS manifestations ... • Tumor lysis syndrome
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