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diagnosis infections hivaids idsa pharmacology prevention infectiousdiseases syndrome differential disease hiv signs symptoms adultonset aids antinxp2 antinxp2dm antiretroviral art arteritis
Initiation of ART in HIV patients with Opportunistic Infections • Pulmonary TB and CD4 cell count
patients with Opportunistic ... count >50 • CNS ... of starting OI treatment ... Therapy #HAART #HIV #Opportunistic ... #Infections #management
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
: • Most CNS opportunistic ... • CNS opportunistic ... Antimicrobial treatment ... - Generally >3 cm ... and <25% culture positive
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
HBV, Coxsackie, CMV ... Muscular: normal CK ... Disease #diagnosis #management ... #treatment #rheumatology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
previously diagnosed opportunistic ... of preexisting opportunistic ... pleural effusions, CNS ... keratitis, iritis • CMV ... Differential #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... +: Virus (EBV, CMV ... or biologics (CMV ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
basal ganglia, CNS ... Skin lesions • Positive ... Arthritis, AS Treatment ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
IDSA Recommendations for Treating Cytomegalovirus Infections in HIV-AIDS Preventing CMV Disease: • CMV end-organ disease is best
ART to maintain CD4 ... ability to adhere to treatment ... whenever feasible, treatment ... effective for treatment ... #management #opportunistic
IDSA Recommendations for Preventing and Treating Toxoplasma gondii Encephalitis in HIV-AIDS Indications for Initiating Primary Prophylaxis: •
Toxoplasma IgG positive ... patients with CD4 ... IDSA #Prevention #Treatment ... #opportunistic ... infections #HIVAIDS #management
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
(at least 1-2 cm ... Biopsies remain positive ... Treatment of GCA ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
/aggregate) of CD4 ... • 8%-27% for CNS ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
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