10 results
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... : • Most CNS opportunistic ... • CNS opportunistic ... and <25% culture positive ... #Infections #differential
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Lymphadenopathy, CNS ... , CD3 Chronic ... Blood #Disorders #hematology ... #Markers #Differential
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin ... Agglutinin Syndrome (CAS ... dehydrogenase • Positive ... younger pts) Differential ... hemolytic #anemia #hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Scleromyxedema (CNS ... +GI+CVS+joints) ... anemia due to cold ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
matter, spinal cord ... basal ganglia, CNS ... Skin lesions • Positive ... Behcet disease) Differential ... signs #symptoms #rheumatology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... pulmonary etc) • CNS ... of the spinal cord ... Up: • Chem: CPK ... #Weakness #Differential
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
previously diagnosed opportunistic ... of preexisting opportunistic ... pleural effusions, CNS ... Leishmaniasis Differential ... Inflammatory #Syndrome #Differential
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
Aspergillus - Other positives ... infection (IFI) in hematologic ... in HM • False positives ... BAL GM does not differentiate ... concurrent admin of mold-active
Upper Motor Neuron (UMN) lesions are lesions occurring anywhere in the CNS from the brain up
anywhere in the CNS ... to the spinal cord ... The lesion could ... form part of the differential ... spasticity, and a positive
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... (symmetric) • CK ... nucleotidase 1A (Anti cN ... Myositis #Myopathy #rheumatology ... #differential #