11 results
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
: • Most CNS opportunistic ... • CNS opportunistic ... required until immune ... Demyelinating disease ... and <25% culture positive
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... fraction < 20% Differential ... Muscular: normal CK ... #diagnosis #management ... #treatment #rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Disease ... Agglutinin Syndrome (CAS ... dehydrogenase • Positive ... younger pts) Differential ... hemolytic #anemia #hematology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
worsening of that disease ... pleural effusions, CNS ... pericarditis, peritoneal disease ... Leishmaniasis Differential ... #Diagnosis #Management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
basal ganglia, CNS ... Skin lesions • Positive ... ) Differential Diagnosis ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
Diagnosis and Management ... impaired cellular immune ... Rhinosinusitis, CNS ... AspGM can be also positive ... vori Infectious Diseases
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... context of primary immune ... and CNS • Headache ... Valvular disorders • CAD ... vein thrombosis Hematologic
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Erythema nodosum • Immune ... Immunohistochemical studies (to differentiate ... number of sites of disease ... classification #hematology ... #oncology #management
Management of Pruritus in Patients with Chronic Kidney Disease
Pruritus with no primary lesions - differential diagnosis:
Management of Pruritus ... Chronic Kidney Disease ... primary lesions - differential ... pruritus • Hematologic ... #Nephrology #CKD
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
without increasing CK ... NXP-2 antibody positive ... had more severe disease ... of anti-NXP-2-positive ... Dermatomyositis #diagnosis #management