11 results
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... CNS Opportunistic ... • CNS opportunistic ... and <25% culture positive ... #differential #
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia 

DIAGNOSTIC CRITERIA FOR ICL
 • Persistent CD4 T-cell lymphopenia
 •
Autoimmune ... chemotherapy) • Genetic syndromes ... • Infections - HIV ... #diagnosis #hematology ... #Differential #
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... necrotizing myopathy • Autoimmune ... parainfluenza, Coxsackie, HIV ... Up: • Chem: CPK ... #Weakness #Differential
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Zone Lymphoma (HCV ... Scleromyxedema (CNS ... Evans • ITP • Cl-NH ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... pleural effusions, CNS ... Leishmaniasis Differential ... #Inflammatory #Syndrome ... #Differential #
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... dehydrogenase • Positive ... Mycoplasma, EBV, HIV ... younger pts) Differential ... hemolytic #anemia #hematology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Infection - Viral (HIV ... Hyperthyroidism - Autoimmune ... Myoglobinuria: UA positive ... Rhabdomyolysis #Differential
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
be any age) Autoimmune ... Can cause TYPE IV ... /aggregate) of CD4 ... • 8%-27% for CNS ... Nephrogenic DI Hematologic
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... disease • Non-autoimmune ... Malignancy (e.g. hematologic ... deficiencies • Autoimmune ... and CNS • Headache
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... weakness + atrophy- Hip ... nucleotidase 1A (Anti cN ... Myositis #Myopathy #rheumatology ... #differential #