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diagnosis neurology rheumatology infections agglutinin aids anemia autoimmune causes cd4 cold disease encephalitis erythematosus hemolytic idiopathic infectiousdiseases inflammatory iris lupus
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
HIV / AIDS - Differential ... CNS Opportunistic ... • CNS opportunistic ... required until immune ... and <25% culture positive
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
primary or secondary immune ... chemotherapy) • Genetic syndromes ... • Infections - HIV ... #diagnosis #hematology ... #Differential #
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Inflammatory Syndrome ... pleural effusions, CNS ... Leishmaniasis Differential ... #Inflammatory #Syndrome ... #Differential #
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Weakness - Differential ... Polymyositis • Immune ... parainfluenza, Coxsackie, HIV ... Up: • Chem: CPK ... #Weakness #Differential
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Zone Lymphoma (HCV ... Scleromyxedema (CNS ... Evans • ITP • Cl-NH ... Paraproteinemias #Hematology ... #Monoclonal #Differential
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework Viral Encephalitis: MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... Herpesviruses (MCC: HSV ... Powassan, louping ill ... Develops in the immune ... Singh @rav7ks #CNS
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis Differential ... chorioretinitis, CNS ... #Vasculitis #Differential ... #Diagnosis #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... context of primary immune ... and CNS • Headache ... vein thrombosis Hematologic ... La, anti-Jo-1, SCL
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... dehydrogenase • Positive ... Mycoplasma, EBV, HIV ... younger pts) Differential ... hemolytic #anemia #hematology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... weakness + atrophy- Hip ... nucleotidase 1A (Anti cN ... Myositis #Myopathy #rheumatology ... #differential #
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