3901 results
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
- Transfusion Reactions ... blood donor • Pathophysiology ... without other cause ... transfusion • Pathophysiology ... #Transfusion #Reactions
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
exposure to allergen causes ... Allergic reaction ... Allergy #Immunology #pathophysiology
Pathogenesis of Rheumatic Fever

Pathogenesis of rheumatic fever. 
1. GAS pharyngitis leads to antigenic presentation of pathogenic
development of cross-reactive ... antibodies and cross-reactive ... activation' by cross-reactive ... antibodies which can cause ... Rheumatic #Fever #Pathophysiology
Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare but potentially serious adverse reaction that has been
serious adverse reaction ... The exact cause ... antibodies which cause ... thrombocytopenia #COVID #pathophysiology
Angiostrongyliasis - Angiostrongylus costaricensis Life Cycle
1) Eggs hatch in the ileum, and first-stage larvae are passed
eggs in tissues causes ... an inflammatory reaction ... LifeCycle #diagnosis #pathophysiology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
hypersensitivity reactions ... - Mechanism of Action ... Allergen-specific lgE causes ... Acute transfusion reaction ... hypersensitivity #reactions
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
hypereosinophilia (HE) Caused ... cytokines Common causes ... : - Drug reaction ... infection - Allergic reaction ... disease Rare causes
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Penicillin-induced drug reaction ... Erythematosus, Reactive ... Dermatitis (ie. reaction ... Allergy #Allergic #Reactions
Antiemetics and Vomiting

#Pathophysiology #Antiemetics #Locations #Action #Pathways #Nausea #Chemotherapy #TriggerZone #CTZ
and Vomiting #Pathophysiology ... Antiemetics #Locations #Action ... #Pathways #Nausea
Differential Diagnosis - Noninfectious Causes of Fever

CRITICAL DIAGNOSES:
 - Acute myocardial infarction
 - Pulmonary embolism or
Noninfectious Causes ... - Transfusion reaction ... - Transplant rejection ... Noninfectious #Causes