14 results
Aortic Dissection Pearls
Aortic dissection is caused by a tear in the tunica intima, the innermost layer
at onset • Tearing ... Marfans, EDS ... valve disease ... #Dissection #diagnosis ... #management #vascular
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal Syndromes ... diseases with pulmonary ... Inflammatory eye disease ... mononeuritis multiplex WORKUP ... #management #treatment
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing
Common causes: 
 • Renal parenchymal disease
- Differential Diagnosis ... Oral sodium loading ... • Cushing’s syndrome ... Hyperthyroidism • Aortic ... Causes #Screening #Workup
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
Differential Diagnosis ... Valvular heart disease ... Congenital heart disease ... Period • Breast-feeding ... teratogenic GDMT meds
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... , PRES Pathophysiology ... inflammation, leading ... #management #treatment
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Shock, Autoimmune disease ... Diagnosis: 1. ... Differential Diagnosis ... Seizures: Treat with AEDs ... #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... highly inflammatory disease ... Excessive release of pro-inflammatory ... IL-1 and IL-6, leading ... #Diagnosis #Management
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... Vasculitis Differential Diagnosis ... < 30 years • Aorta ... asymmetric arm BP readings ... Arteritis): • Aorta
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup ... and Differential Diagnosis ... Coarctation of aorta ... Renal parenchymal disease ... #Hypertension #Workup
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
and Management ... positive in 2/3 of pts ... antibody that works ... Baclofen • Severe Disease ... #Management #treatment