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hematology differential aortic cell cerebritis classification dissection erythematosus hearing histiocytosis hodgkins langerhans lch leukemia loss lupus lymphoma mds monoclonal myelodysplasia
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Cerebrovascular Disease ... thrombosis and/or blood-brain ... #neurology #rheumatology ... #management #treatment
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... et diutinum Neurologic ... Sneddon-Wilkinson disease ... #Differential #Diagnosis ... #Oncology
Hearing Loss - Differential Diagnosis Framework Hearing Loss Types: • Conductive • Sensorineural • Mixed Presbycusis is the most common type
Diagnosis Framework ... include a: • Neurologic ... auditory nerve (CN ... Mitochondrial disorders ... ○ HIV ○ Lyme disease
Aortic Dissection Pearls Aortic dissection is caused by a tear in the tunica intima, the innermost layer
Connective tissue disorder ... • Aortic valve disease ... ~60 • Control blood ... Aortic #Dissection #diagnosis ... #management #vascular
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
on bone marrow leading ... extramedullary disease ... involvement • 30%: CNS ... leukostasis syndrome: CNS ... #Oncology #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... Myeloproliferative Disease ... Neutropenia • Platelet Disorders ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... Workup: • Full Blood ... marrow biopsy - if blood ... number of sites of disease ... #oncology #management
Langerhans Cell Histiocytosis (LCH) Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
LCH is a rare disorder ... CNS involvement: ... DIAGNOSIS • Imaging ... Laboratory Tests: Blood ... #Management
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