26 results
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Indications and Pharmacology ... Inhibits plasminogen activation ... reduces complement activation ... Hypotension with rapid injection ... #hematology
Here is a quick guide on the common direct-acting antivirals (DAAs) for chronic hepatitis C virus
C virus (HCV) infection ... Antivirals #table #treatment ... infectiousdisease #hepatology ... HepatitisC #Management #Pharmacology
COVID-19 review…here is a list of some of the drugs that are currently being used or
announced it is leading ... most effective treatments ... #CoronaVirus #Treatment ... Pharmacotherapy #Pharmacology ... #CriticalCare #
Eosinophilic Gastroenteritis: Treatment Options Based on Severity of the Disease
Mild:
 • Trial of PPI
 • Trial
Gastroenteritis: Treatment ... consultation for non-healing ... Concern for HES: • Hematology ... Gastroenteritis #Treatment ... #management #gastroenterology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... Coagulation Failure Infections ... Failure #Cirrhosis #Hepatology ... #gastroenterology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
excessive macrophage activation ... can mimic common infections ... • Bicytopenia Treatment ... : • Infection ... #hematology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
• Endogenous reactivation ... involvement - seeding ... Tuberculosis Treatment ... Initiating Treatment ... Diagnosis #Management #Treatment
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... DOACs thereby leading ... metabolization leading ... Chemotherapy #Oncology #Hematology ... Interactions #Table #Pharmacology
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
with chronic HBV infections ... absent the risk of reactivation ... Chronic Hepatitis B Infection ... Diagnosis #Management #Treatment ... #Hepatology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
• Endogenous reactivation ... involvement - seeding ... Tuberculosis Treatment ... Initiating Treatment ... Diagnosis #Management #Treatment