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diagnosis hematology abnormal bruising prolonged pt thrombocytopenia disorders extravascular hemolysis hemolytic hemostasis intravascular pediatrics peds platelet purpura workup
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Pre-analytical cause ... (DIC) c. ... #Prolonged #Causes ... #diagnosis #differential
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... the PT and the aPTT ... intravascularcoagulation (DIC ... #diagnosis #differential ... #hematology #coagulation
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... intravascular coagulation ... (DIC) - HELLP ... Extravascular #Causes ... #differential #
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... - History of bleeding ... : INR/PT, aPTT(liver ... function test, ANA (e.g ... changes), high MCV anemia
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
of Hemostasis - Differential ... inhibitor of a coagulation ... Warfarin • Acute DIC ... discern these causes ... disease • Acute DIC
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... purpura - DIC ... intravascular coagulation ... Purpura #Bruising #Causes ... pediatrics #diagnosis #differential
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