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diagnosis hematology abnormal bruising prolonged pt purpura thrombocytopenia bleeding cardiology chf deficiency dermatology extravascular heartfailure hemolytic hemostasis high intravascular iron
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... intravascular coagulation ... (DIC) - HELLP ... lymphoproliferative disorders ... #differential #
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... , coagulation disorders ... disorders CAUSES ... /TTP/HUS - Hemolytic ... anemia - Splenomegaly
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Pre-analytical cause ... (DIC) c. ... #Prolonged #Causes ... #diagnosis #differential
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... the PT and the aPTT ... intravascularcoagulation (DIC ... #diagnosis #differential ... #hematology #coagulation
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
- Differential ... malignancies • Anemia ... iron deficiency, hemolysis ... Chronic inflammatory disorders ... (e.g. autoimmune
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential ... : INR/PT, aPTT(liver ... function test, ANA (e.g ... changes), high MCV anemia ... #Differential #
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Diet: ↓ Intake, e.g ... hepcidin) • Others: Hemolysis ... Iron metabolism disorders ... #differential # ... diagnosis #anemia
High Output Heart Failure - Pathophysiology and Differential Diagnosis Obesity - Systemic Vasodilation, Vasoactive Adipokines Arteriovenous Fistula -
Pathophysiology and Differential ... Systemic Vasdilation, AV ... Myeloproliferative Disorders ... Metabolism Severe Anemia ... Diagnosis #cardiology #causes
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
of Hemostasis - Differential ... inhibitor of a coagulation ... Warfarin • Acute DIC ... discern these causes ... disease • Acute DIC
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... purpura - DIC ... intravascular coagulation ... Purpura #Bruising #Causes ... pediatrics #diagnosis #differential
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