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diagnosis hematology purpura bruising deficiency dermatology extravascular hemolysis intravascular nonpalpable nutrition palpable pediatrics peds rheumatology secondary thrombocytopenia thrombocytosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... intravascular coagulation ... (DIC) - HELLP ... lymphoproliferative disorders ... #differential #
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Causes of Iron Deficiency ... hepcidin) • Others: Hemolysis ... disorders Dr. ... #differential # ... diagnosis #anemia
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... , coagulation disorders ... disorders CAUSES ... /TTP/HUS - Hemolytic ... anemia - Splenomegaly
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
malignancies • Anemia ... (specifically: iron ... deficiency, hemolysis ... Chronic inflammatory disorders ... (e.g. autoimmune
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... purpura - DIC ... intravascular coagulation ... Purpura #Bruising #Causes ... pediatrics #diagnosis #differential
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