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diagnosis differential coagulation abnormal algorithm bleeding bruising disseminated hemostasis management obgyn obstetrics postpartum pph thromboticthrombocytopenicpurpura treatment ttp workup
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
PT and/or aPTT ... PT and aPTT 1. ... Disseminated intravascular ... coagulation (DIC ... #aPTT #Prolonged
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
PT and aPTT If ... aPTT are both prolonged ... • Massive hemorrhage ... #aPTT #Prolonged ... #differential #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... Thrombocytopenia • Prolonged ... PT/PTT • Low ... INR < 2.3 - APTT ... #Disseminated #Intravascular
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm Blood Loss: >500mL post vaginal delivery OR >1000 mL
Causes of Post-Partum ... Hemorrhage - Differential ... . prolonged/induced ... • Disseminated intravascular ... coagulation (DIC
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
prolonged after ... , disseminated intravascular ... discern these causes ... disease • Acute DIC ... Differential #Diagnosis #Hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
be performed PT ... , PTT, and fibrinogen ... ; hemorrhage and ... reflection of intravascular ... Diagnosis #Workup #Hematology
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