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diagnosis antidrugantibodies antitnffailure checkpointinhibitor colitis druglevels fatigue gi immune resistance
Algorithm for managing the failure of anti-TNF therapy. ADA=anti-drug antibody; IM=immunomodulator; MOA=mechanism of action; TNF=tumor necrosis
Algorithm for managing ... necrosis factor #Management ... #GI #IM #IBD #AntiTNFFailure ... AntiDrugAntibodies #DrugLevels #Algorithm ... #BMJ
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
Algorithm • 40- ... /other causes • ... modifications Algorithm ... #Algorithm #diagnosis ... #management
Immune Checkpoint Inhibitor-Mediated Colitis Grade of Disease Severity: • G1: Increase < 4 BMs/day over baseline; mild
: Increase < 4 BMs ... : Increase 4-6 BMs ... indicated Diagnostic Evaluation ... Colitis #diagnosis #management ... #algorithm #IBD
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