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differential management rheumatology leukemia workup algorithm chronic hepatology hodgkins lymphocytic lymphoma monoclonal thrombocytopenia abnormal agglutinin anemia apml ascites behcet bowel
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL Symptoms: ... extramedullary disease ... ) CLL Symptoms: ... #Leukemia #Hematology ... #Oncology #Diagnosis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Differential Diagnosis ... Lymphomas • Other hematologic ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Diagnosis: • ... cells can indicate disease ... #workup #oncology ... #hematology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
ULN R - Renal disease ... diseases, CML, ... plasmacytoma, POEMs syndrome ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... lymphoid malignancy (CLL ... significance (MGUS), CLL ... hemolytic #anemia #hematology ... #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytic Leukemia (CLL ... minimal tumor burden Diagnosis ... chemotherapy for low-risk disease ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... : >3 symptoms, or ... dysfuxtion, ICU, refractory ... #management #hematology ... #oncology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
meningitis), MCC CNS symptoms ... ) Differential Diagnosis ... azathioprine • Severe or refractory ... #signs #symptoms ... #rheumatology #
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... PT, aPTT(liver disease ... pylori test (GI symptoms ... not required in all ... Refractory ITP,
Irritable Bowel Syndrome (IBS) - Diagnosis and Workup Summary Use a positive diagnostic strategy with minimal testing.
Irritable Bowel Syndrome ... last 3 months + symptom ... Rule out celiac disease ... inflammatory bowel disease ... Disorder &/or Refractory
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