10 results
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Primary Biliary Cirrhosis ... - Pathophysiology ... female-predominant disease ... of autoimmune disease ... Primary #Biliary #Cirrhosis
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
) Pathophysiology ... • Autoimmune diseases ... Adult-onset Still disease ... Unknown cause Treatment ... diagnosis #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
) Treatment Primary ... or autoimmune disease ... , treatment of underlying ... transplantation for refractory ... disease - Dr.
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Syndrome Systemic disease ... common in Asia • HLA-B51 ... Inflammatory eye disease ... Arthritis, AS Treatment ... azathioprine • Severe or refractory
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
malignancy Pathophysiology ... adenoma, ↓(TFT, LH ... Radiotherapy: Relapse or refractory ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
adenomas that require treatment ... following order; GH, LH ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
diagnosis and treatment ... Hemochromatosis HH ... with suspected HH ... Patients with cirrhosis ... causes of liver disease
Hepatopulmonary Syndrome - Illness Script
HPS is a pulmonary disorder of chronic liver disease characterized by a
abnormalities PATHOPHYSIOLOGY ... • Stigmata of cirrhosis ... the left heart TREATMENT ... only definitive treatment ... Hepatopulmonary #Syndrome #cirrhosis
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
multicentric Castleman disease ... , Lyme disease, ... IGG4 - Hepatic cirrhosis ... cell lymphoma Pathophysiology ... Hypoalbuminemia Treatment
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
extrapulmonary disease ... or meningitic disease ... , neutropenia, cirrhosis ... Aspergillosis Pathophysiology ... 40% Invasive Disease