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management diagnosis hemophagocytic lymphohistiocytosis rheumatology acromegaly fungal hematology infectiousdiseases mycoses summary tafro thrombocytopenia
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
) Pathophysiology ... • Autoimmune diseases ... Adult-onset Still disease ... Unknown cause Treatment ... diagnosis #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
) Treatment Primary ... associated with infection ... or autoimmune disease ... transplantation for refractory ... disease - Dr.
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
malignancy Pathophysiology ... adenoma, ↓(TFT, LH ... Radiotherapy: Relapse or refractory ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
extrapulmonary disease ... or meningitic disease ... , neutropenia, cirrhosis ... Aspergillosis Pathophysiology ... 40% Invasive Disease
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
vasculitis - Infectious ... fast bacterial infection ... IGG4 - Hepatic cirrhosis ... cell lymphoma Pathophysiology ... Hypoalbuminemia Treatment
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