7 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
) Pathophysiology ... • Autoimmune diseases ... Unknown cause Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
) Treatment Primary ... or autoimmune disease ... transplantation for refractory ... disease - Dr. ... #Treatment #management
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
malignancy Pathophysiology ... adenoma, ↓(TFT, LH ... Radiotherapy: Relapse or refractory ... #Endocrinology ... #Treatment #Pathophysiology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Syndrome Systemic disease ... common in Asia • HLA-B51 ... Arthritis, AS Treatment ... azathioprine • Severe or refractory ... Syndrome #diagnosis #management
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
diagnosis and treatment ... Hemochromatosis HH ... Patients with cirrhosis ... causes of liver disease ... algorithm #diagnosis #management
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
, Lyme disease, ... IGG4 - Hepatic cirrhosis ... cell lymphoma Pathophysiology ... Hypoalbuminemia Treatment ... TAFRO #diagnosis #management
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
extrapulmonary disease ... or meningitic disease ... , neutropenia, cirrhosis ... Aspergillosis Pathophysiology ... Fungal #Diagnosis #Management