13 results
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Vaughan Williams Classification ... CLASS 3 - Potassium ... prolong AV node repolarization ... #Pharmacology #Classification ... #Classes #pathophysiology
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... prolong AV node repolarization ... CLASS 3 - Potassium ... #Pharmacology #Classification ... #Classes #pathophysiology
Hypokalemia - Differential Diagnosis
Poor Intake 
 - Starvation
 - Anorexia
GI Losses 
 - Vomiting / NG
Hypokalemia - Differential ... and 2, but not type ... Diagnosis #Low #Potassium ... #Table #Classification ... #Causes
Hyperkalemia shortens repolarization; changes in the T wave provide the earliest clues to hyperpotassemia.
 - At
repolarization; ... changes in the ... causes peaked T ... in conduction causes ... #Progression #Table
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... Differential Diagnosis Algorithm ... tubular acidosis (type ... #causes #nephrology ... #potassium
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• Recent IV potassium ... Failure • SLE • Type ... kiwis, mangoes, oranges ... differential #diagnosis #causes ... #potassium #high
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• Recent IV potassium ... Failure • SLE • Type ... kiwis, mangoes, oranges ... differential #diagnosis #causes ... #potassium #high
Causes of Hyperkalemia
l. Pseudohyperkalemia
  A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis
  B.
Causes of Hyperkalemia ... Pseudohypoaldosteronism type ... Diagnosis #High #Potassium ... #Classification ... #Causes
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Aldosterone, RTA Type ... only if no clear cause ... Elimination (see Table ... K-Binding Resins - Exchanges ... Management #Treatment #potassium
Evaluation and Management of Hypokalemia

Hypokalemia is often asymptomatic. Evaluation begins with a search for warning signs
Hypokalemia is ... palpitations, changes ... Most cases of hypokalemia-induced ... depletion impedes potassium ... #Evaluation #Algorithm