8 results
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Phase I - Initial Repolarization ... - Ventricular Repolarization ... Vaughan Williams Classification ... #Pharmacology #Classification ... #Classes #pathophysiology
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... prolong AV node repolarization ... prolong AV node repolarization ... #Pharmacology #Classification ... #Classes #pathophysiology
Hyperkalemia shortens repolarization; changes in the T wave provide the earliest clues to hyperpotassemia.
 - At
Hyperkalemia shortens ... repolarization; ... changes in the ... causes peaked T ... #Progression #Table
Hypokalemia - Differential Diagnosis
Poor Intake 
 - Starvation
 - Anorexia
GI Losses 
 - Vomiting / NG
Hypokalemia - Differential ... and 2, but not type ... Low #Potassium #Table ... #Classification ... #Causes
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Weakness, cramping, nausea ... Aldosterone, RTA Type ... only if no clear cause ... Elimination (see Table ... K-Binding Resins - Exchanges
Causes of Hyperkalemia
l. Pseudohyperkalemia
  A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis
  B.
Causes of Hyperkalemia ... Pseudohypoaldosteronism type ... pseudohypoaldosteronism type ... High #Potassium #Classification ... #Causes
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
-60y (hormonal changes ... survival is 93-95% Pathophysiology ... hyperphosphatemia, hypercalcemia ... symptoms are not caused ... Self-limiting, chronic but stable
6/02/2022 UPDATE: This assay is designed to detect non-variola orthopoxviruses, including monkeypox virus. It is not
2022-lab-advisory-CLARIFICATION-CDC_Publishes_Non-variola_Orthopoxvirus_PCR_Testing_Procedure ... should use this algorithm ... smallpox-diagnostic-algorithm-poster ... The type of specimen ... See table below