5 results
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... Polymyositis and dermatomyositis ... polyangiitis without renal ... Antineutrophil #antibodies ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Still disease, dermatomyositis ... Non-autoimmune rheumatologic ... APLA/LAC: • Renal ... 1, SCL-70, RNP antibodies ... anticardiolipin antibodies
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
Antibodies targeting ... chest (in a V-sign ... shoulders (in a shawl sign ... • Clear cell renal ... diagnosis #management #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
levels • EMG DERMATOMYOSITIS ... RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... Myositis #Myopathy #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
pulmonary and renal ... purpura: strong sign ... C-ANCA) pattern: antibodies ... • Urinalysis (Renal ... differential #diagnosis #rheumatology