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diagnosis differential lupus sle systemic vasculitis antinxp2 antinxp2dm champs classification complement dermatology dermatomyositis diabetes diabeticketoacidosis endocrinology hematology hypocomplementemia low management
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Systemic Lupus Erythematosus ... (total 50, renal ... subacute bacterial endocarditis ... #differential #hematology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Pericarditis, Endocarditis ... Abdominal pain (20%) Renal ... SLE #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Ketoacidosis (DKA ... Findings • Note: in DKA ... patient has good renal ... Signs/Symptoms/Complications ... #pathophysiology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... • Libman-Sacks endocarditis ... APLA/LAC: • Renal ... and C4) • ds-DNA ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pulmonary and renal ... systemic lupus erythematosus ... purpura: strong sign ... • Urinalysis (Renal ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulmonary and renal ... purpura: Strong sign ... ischemia • Skin: Erythematous ... Differential #Diagnosis #Rheumatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
with edema • Erythematous ... chest (in a V-sign ... shoulders (in a shawl sign ... • Clear cell renal ... diagnosis #management #rheumatology
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